Decline in the use of erythropoiesis-stimulating agents: Long-term effects of regulation, reimbursement, and unfavorable data. Effect of a topoisomerase-1 inhibitor (topotecan) on the efficacy of ...

We conducted a multicenter, open-label, randomized, controlled trial with a two-group, parallel, group-sequential design. During a 6-month run-in phase, supportive care (in particular, blockade of the ...

Riluzole is a glutamate-modulating agent with neuroprotective properties approved for use in amyotrophic lateral sclerosis. The efficacy and safety of riluzole vs placebo as an adjunct to ...