In genomewide linkage scans for complex diseases involving many loci with small genetic effects, it may be the case that no loci reach conventional statistical significance. A complementary method of ...

As cost per base continues to decrease for next-generation sequencing, genotyping-by-sequencing becomes a practical solution for high- throughput studies. However, addressing genomic complexity ...

Errors in genotyping can substantially influence the power to detect linkage using affected sib-pairs, but it is not clear what effect such errors have on quantitative trait analyses. Here we use ...