The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and ...

Researchers have uncovered a previously hidden layer of complexity in how genes are activated, showing that water molecules ...

EM, researchers showed that water mediates catalysis and important protein interactions for RNA polymerase II function in ...

A collaboration of scientists at the University of Manchester and the University of Birmingham has explored a more effective ...

Gene expression and pathway analysis constitute a critical nexus in modern molecular biology, facilitating the exploration of how genes collectively influence cellular functions and disease processes.

Why do brain disorders affect men and women differently? Researchers used RNA sequencing to identify 3,000 sex-biased genes in the human cortex linked to psychiatric risk.

Study reveals how aging accelerates molecular changes in the brain, offering new hope for tackling cognitive decline and mental illness. Resource: Single-nucleus transcriptomic profiling of human ...

A collaborative effort has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of ...

Scientists are uncovering the intricate ways our genes turn on and off, shaping everything from butterfly wings to cancer therapies. Advances in single-cell analysis, epigenetic mapping, and AI-driven ...

What do your genes have to do with growing old? Quite a lot. But is it due to the actual DNA, or the way those genes are expressed? KPBS sci-tech reporter Thomas Fudge has more on new research that ...

Computational assessment identifies probe binding errors in a widely used commercial platform for spatial transcriptomics.