Gene expression and pathway analysis constitute a critical nexus in modern molecular biology, facilitating the exploration of how genes collectively influence cellular functions and disease processes.

Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

Using genomic and transcriptional data has greatly improved the understanding of multiple aspects of human physiology. A new paper in PNAS reports on molecular-level associations of co-occurring ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Stay up to date on the latest science with Brush Up Summaries. Finally, although transgenic animals and mammalian cell culture systems promote optimal expression due to correct protein modifications, ...

Studying gene expression in a cancer patient's cells can help clinical biologists understand the cancer's origin and predict the success of different treatments. But cells are complex and contain many ...

Discover how circular RNA technology enhances gene expression by up to 50-fold in eye treatments, surpassing traditional ...

Plant breeding has contributed to the sustainability of crop production since antiquity and is expected to play an increasingly important role in the ...

Genetics is the study of genes and how they influence characteristics and health. Through a variety of technological methods, environmental factors, and lifestyle choices, it is possible to alter some ...