The spliceosome is a dynamic macromolecular machine responsible for the precise excision of introns from pre-messenger RNA (pre-mRNA), thereby enabling the accurate formation of mature mRNA. Comprised ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

Section 1. Purpose. Dangerous gain-of-function research on biological agents and pathogens has the potential to significantly endanger the lives of American citizens. If left unrestricted, its effects ...

Stanley is an associate professor and Richard and Rhoda Goldman distinguished chair in the biological sciences as well as faculty director for the Alliance for Global Health and Science at the ...