βig-h3 is a TGF-β-induced extracellular matrix protein which is expressed in many tissues including bones and cartilages. In previous reports, we showed that βig-h3 mediates cell adhesion and ...

Retinoic acid receptors inhibit chondrogenesis, but their ability to block the cartilaginous scaffold of heterotopic endochondral ossification has not been explored. A study in mice shows that ...

"Historically viewed as mainly a “wear and tear” condition, new insights suggest that OA may be part of an evolutionary, age-related biological process rather than mainly driven by mechanical damage." ...