Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

Researchers have used naïve pluripotent stem cells to create an embryo model that looks and acts like a natural human embryo. They say it’s an ethical way of gaining a better understanding of ...

A new study from the MRC Laboratory of Medical Sciences (LMS) in London, UK reveals how ancient viral DNA once written off as ...

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

Researchers have discovered a potential 'pause button' in the earliest stages of human development. Whether humans can control the timing of their development has long been debated. The new study ...

Two to three weeks after conception, an embryo faces a critical point in its development. In the stage known as gastrulation, the transformation of embryonic cells into specialized cells begins. This ...

The new organoids were grown in the lab for up to 40 days, and they mimicked the central nervous system of an 11-week-old human embryo. When you purchase through links on our site, we may earn an ...

From the moment an embryo starts to take shape, two-way communication is critical for making sure tissues and organs develop ...

The viral transposable element, MERVL, acts as a central switch during early embryonic development, driving totipotent gene ...