Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some ...

Researchers have used naïve pluripotent stem cells to create an embryo model that looks and acts like a natural human embryo. They say it’s an ethical way of gaining a better understanding of ...

What do the earliest stages of a pregnancy look like? Embryonic development has been extensively studied, but most of our knowledge of the earliest stages of a growing baby come from stationary ...

As described in research published today in Cell, the new model can be used to study the origin and function of the human amnion and help identify previously unknown ways the amniotic sac might ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable ...

BEIJING -- After years of dedicated research, a team of Chinese scientists has unveiled critical mechanisms governing early human embryonic development, offering novel theories and potential ...

In a new study, researchers compare the transcriptomic profiles of recently reported human embryo stage 8-cell-like cells with human embryos The onset of embryo-specific gene transcription, also known ...

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four ...