The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some ...

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

As described in research published today in Cell, the new model can be used to study the origin and function of the human amnion and help identify previously unknown ways the amniotic sac might ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

What do the earliest stages of a pregnancy look like? Embryonic development has been extensively studied, but most of our knowledge of the earliest stages of a growing baby come from stationary ...

New international research shines a light on the role of transcription factors during early embryonic development. Transcription factors are proteins that are critical for gene regulation. The study ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

The discovery of a gene essential to early embryonic development sheds light on the preliminary stages of human placenta formation. A team led by scientists from the University of California San Diego ...

SCDIRB copy 39088019634765 not included in the Bibliotheca Beckwithiana (unpublished). SCDIRB copy has bookplate: Smithsonian Libraries: The Beckwith-Browning-Peterson Teratology Collection. SCDIRB ...

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four ...