A novel genome editing technique, NICER, is based on the creation of multiple nicks in single DNA strands by nickase. The method can correct heterozygous mutations using two mechanisms: multiple nicks ...

For the first time, scientists have found a way to efficiently and precisely remove genes from white blood cells of the immune system and to substitute beneficial replacements, all in far less time ...

In a major step toward treating rare neurological diseases, scientists have used gene editing to correct mutations inside the brain of living mice with a single injection. This new approach, described ...

Researchers have developed a single genome-editing strategy, known as PERT, that could potentially treat various diseases caused by nonsense mutations.

Researchers at the Francis Crick Institute have demonstrated that a genetic method called "pooled prime editing" can screen hundreds of variants in a gene at once and identify which variants affect ...

Researchers have developed a new “color-coded” genetic method that makes it easy to distinguish male and female mosquitoes. This innovation can help solve a major bottleneck in mosquito control ...

'Our new but simple method is far more effective and can now be applied to a much wider range of plant species than our original approach' Genetically modified organisms, also known as GMOs, have been ...

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited ...

Chemists have developed an efficient skeletal editing method for frequently used heteroaromatic structures. The technique could serve as a means to chemically modify biologically active compounds.