For biologists, seeing is believing. But sometimes biologists have a hard time seeing. One particularly vexing challenge is seeing all the molecules in an intact tissue sample, down to the level of ...

The human body and its organs are composed of a wide variety of cell types. Although all cells contain the same genes, they function very differently—partly because protein interactions differ between ...

Scientists from Gladstone Institutes developed a computational approach that accurately distinguishes cells of different identities or characteristics in complex biological samples used in diverse ...

Dissociating tissues into single cells is a core laboratory technique and vital for widely used applications such as next-generation sequencing or flow cytometry. Scientists who employ tissue ...

Nucleic acid extraction from biological samples is inherently difficult to execute consistently across different tissue types. Some tissue matrices are fibrous, contained in protective cell walls, or ...

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists, ...

TEMI mapping of lipid distribution across cerebellar layers. This image shows lipid species specifically enriched in three distinctive layers of the cerebellum: molecular layer, white matter layer and ...