DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.
Researchers have identified the specific structural loops in G-quadruplex DNA that allow it to act as a chaperone, preventing ...
DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...
Scientists from the 4D Nucleome Consortium at UMass Chan Medical School mapped the human genome in 3D over time, uncovering ...
The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...
This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...
For James Watson, DNA was everything — not just his life's work, but the secret of life itself. Over his long and storied career, Watson arguably did more than any other scientist to transform a ...
His decoding of the blueprint for life with Francis H.C. Crick made him one of the most important scientists of the 20th century. He wrote a celebrated memoir and later ignited an uproar with racist ...
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