The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

DNA methylation is a widely studied epigenetic modification with crucial roles in gene regulation, development, and disease, particularly in cancer. It has immense potential as a biomarker for early ...

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...