Children living in war-torn countries not only suffer from poor mental health outcomes, but war may cause adverse biological changes at the DNA level, which could have lifelong health impacts, ...
DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...
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New function of DNA repair protein ATR discovered
Researchers at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena have discovered a new function of the DNA repair protein ATR in regulating mitochondrial homeostasis. This discovery ...
A system once tied to DNA organization in cyanobacteria has evolved into a structure that shapes the cell itself. This shift ...
A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...
A team of Israeli researchers has found that one of the reasons that sleep could be so important to animals — including humans — is that it takes neurons 'offline' so DNA damage accumulated during ...
Preclinical studies have highlighted how (E,E)-bisantrene silences c-MYC gene expression via G4-DNA binding and stabilization leading to clinically relevant and broad anticancer activity ...
In the first study of its kind, the research team collected saliva samples from 1,507 Syrian refugee children, aged 6 to 19, living in informal settlements in Lebanon. They analysed DNA methylation ...
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