Finding a life-changing drug molecule is like playing the lottery — only one out of several million candidate organic molecules that are initially screened might progress through preclinical studies ...
Aromatic ketones have long been valuable intermediates in chemical synthesis, particularly in cross-coupling reactions where different chemical entities are combined to form new compounds. For ...
Professor Pei-Qiang Huang's research group at Xiamen University recently reported the first reduction-cross-coupling reaction of aliphatic tertiary ...
It’s hard to improve on a classic. But Richard Y. Liu was eager to take on that challenge. Cross-coupling reactions, including Suzuki-Miyaura coupling and Buchwald-Hartwig amination, are some of the ...
Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...
According to a study published in Nature Communications, a research team led by Associate Professor Jiong Lu from the Department of Chemistry at the National University of Singapore devised an ...
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