"Organoids offer a means to connect genetic and environmental alterations relevant to neuropsychiatric disorders with specific early cortical patterning events." A new model for cortex development ...

Epilepsy is present in 4% of the population, and is among the most common brain disorders in children. Modern medicine can prevent most seizure recurrences, but approximately 20% of patients do not ...

A new study finds key differences in the development of the cortex between autistic boys and girls ages 2-13. The study found sex-specific changes in the thickness of the outer layer of the brain, ...

The morphogenesis of brain folding patterns across species is studied by physical gel models, simulations, and a quantitative morphometric analysis.

Normal cortical development with PRC2 (upper image) vs. irregular cortical development without PRC2 (lower image). Different colors stand for different maturation stages of cortical stem cells and ...

Physical gel models and numerical simulations have been created to study ferret brain gyrification and cortical malformations, while comparisons with human phenotypes aim to link genetics and brain ...

A Japanese research team has successfully reproduced the human neural circuit in vitro using multi-region miniature organs known as assembloids, which are derived from induced pluripotent stem (iPS) ...