Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with light and dark exposure. Disruptions in the rhythms of these clocks, as with ...

Researchers developed PRINCE, a small-molecule-controlled CRISPR system enabling precise, long-term regulation of gene editing.

On the left is a snapshot of single histone molecules (red) inside a cell nucleus (dotted line). On the right, we see the trajectories of these molecules’ movement over time. The colors show the path ...

Not all parts of our genetic code are equal, even when they appear to say the same thing. Scientists have discovered that cells can detect less efficient genetic instructions and selectively silence ...

Chronic alcohol consumption profoundly alters gene expression in key brain regions involved in reward, impulse control, and decision-making, according to a study led by researchers at the Institute ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

For more than a century, heredity has been framed through the tidy logic of Mendel’s pea plants: traits pass from parent to ...

A molecule once thought to be a harmful metabolic byproduct may play a crucial role in early development and gene regulation, ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the ...