The authors discuss the advantages of microreactors and flow chemistry for various reaction types in achieving improved process economics and reaction efficiency. This article is part of PharmTech's ...

Continuous twin-screw granulation offers several options for increasing production scale. Thermo Fisher Scientific explains factors to consider in scale-up projects for manufacturing oral solid-dosage ...

At the just completed BioProcess International Conference in Boston, a number of sessions focused on the Bioprocess 4.0 trend toward continuous bioprocessing operations. Akshat Mullerpatan, PhD, ...

Companies choose manufacturing processes -- such as job order, batch process, assembly line and continuous process -- based in part on the level of product individualization allowed. Manufacturers use ...

Batch process scheduling and optimisation is a critical area of research that addresses the timing, sequencing, and allocation of production tasks in industries where manufacturing is carried out in ...

Lyophilization model can help optimize freeze-drying steps for continuous manufacturing processes, according to MIT researchers.

Liquid-liquid Extraction (LLE) is an often overlooked process step that can lead to different bottlenecks during scale up and production of a wide range of pharmaceuticals, fine chemicals and ...

At a recent meeting in Boston, representatives from global pharmaceutical companies gathered to discuss how to transition from batch to continuous manufacturing. And what company better to learn from ...

ISA106 started with the goal of developing standards, recommended practices, and technical reports on the design and implementation of procedures for automating continuous process operations. The ...

This article overviews some of the benefits and methods of state-based control as it applies to the models defined by the ISA106, Procedure Automation for Continuous Process Operations standards ...