Medical researchers have discovered a new regulator of the blood coagulation cascade. Researchers at the George Washington University School of Medicine and Health Sciences (SMHS) have discovered a ...

The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

image: (top) Citrated whole blood is put between electrodes. When the blood starts coagulation, the permittivity measured by alternating current (AC) increases in relation to the aggregation and ...

CRP, C-reactive protein; F, factor; IL-6, interleukin 6; NO, nitric oxide; PAI-1, plasminogen activator inhibitor-1; ROS, reactive oxygen species; TNF-α, tumor ...

Under homeostatic conditions, the body is maintained in a finely tuned balance of coagulation and fibrinolysis. See Figure 1 for a depiction of normal hemostasis. The activation of the coagulation ...

Our innate coagulation – or clotting – cascade is quite a dynamic, but formidable system. When optimally effective, it manages retention of a balanced condition between not too much bleeding and not ...

Thrombosis is a harmful activation of the clotting process, which is associated with the occurrence of blood vessel-related diseases. Pathological enhancement of the clotting cascade causes thrombosis ...