Nerve cells communicate with each other by means of electrical impulses. To create such an impulse, the cells exchange charged ions with their environment. However, the role played by the ever-present ...

Chloride channels are integral membrane proteins that facilitate the passage of chloride ions across cellular membranes, contributing fundamentally to cell volume regulation, transepithelial transport ...

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out ...

Laboratory cell experiments and computer simulations have revealed molecular mechanisms regulating a protein channel responsible for transporting chloride and other charged molecules across cell ...

The cell membranes of nerve cells, like those of all other cell types in the body, are perforated by so-called chloride channels. These permit the exchange of negatively charged chloride ions between ...

In the cells of the Arabidopsis plant, exposure to sodium chloride (NaCl) induces the movement (translocation) of the green fluorescent protein (GFP) tagged chloride channel, GFP-AtCLCf, from the ...

When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a ...

Laboratory cell experiments and computer simulations have revealed molecular mechanisms regulating a protein channel responsible for transporting chloride and other charged molecules across cell ...

NMD Pharma A/S, a clinical-stage biotech company dedicated to developing novel and improved treatments for patients living with neuromuscular diseases, today announces that Thomas Holm Pedersen, Chief ...

Credit: Shutterstock. NMD670 is a first-in-class small molecule inhibitor of the skeletal muscle specific chloride ion channel. The Food and Drug Administration (FDA) has granted Orphan Drug ...