Researchers have developed an animal model that reproduces motor dysfunction and cerebellar neurodegeneration similar to that in spinocerebellar ataxia (SCA) by inhibiting chaperone-mediated autophagy ...

The cerebellum plays a role in prefrontal cortex (PFC) function and cognition. How chronic and progressive cerebellar dysfunction impacts PFC function and cognition remains less understood.

Reduction in mitochondrial activity in multiple sclerosis contributes to Purkinje cell loss. Researchers at the University of California, Riverside (CA, USA) have demonstrated the role mitochondrial ...

Multiple sclerosis (MS) is a chronic inflammatory disorder that is thought to impact about 2.3 million people around the world. This disorder is characterized by the loss of a protective neuronal ...