The latent reservoir for HIV-1 in resting CD4⁺ T cells is a major barrier to cure. Several lines of evidence suggest that the latent reservoir is maintained through cellular proliferation. Analysis of ...

Researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells. University ...

Researchers uncover the first piece of functional evidence suggesting that Tulane virus and human norovirus use viroporins to control cellular calcium signaling. Some gastrointestinal viruses need ...

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to ...

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in ...

New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

Ever hear someone say that every human has cancer at a given moment in time? Although clinically undetected cancers are common, the natural defenses of your body often eliminate abnormal cells before ...