Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...

Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

In single-cell research, understanding how stochasticity in gene transcription influences phenotypic heterogeneity within isogenic cell populations represents a fundamental question. Fluctuations in ...