A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...
One of the most widely accepted models for how cells remember their identity may be incorrect. This is shown in a new study ...
By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...
Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...
To model bacterial life, Thornburg and his colleagues turned to one of its simplest examples: a bacterial cell with a ...
Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...
Mor than 800 million people worldwide are living with diabetes, according to World Health Organization (WHO) estimates, with numbers steadily increasing. Diabetic patients experience abnormally high ...
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Intestine-mimicking cell model accurately predicts drug toxicity
A cell model that replicates the structure and function of the human intestine has been developed, creating an evaluation platform capable of more accurately predicting adverse effects of new drugs.
Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance, published in ...
Vertex Pharmaceuticals and bluebird bio have entered into an agreement with CMS to participate in a new Medicaid payment model for gene-based sickle cell anemia treatments, the agency announced ...
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