The regulation of the cell cycle is a fundamental process ensuring the accurate replication and division of cells. Central to this regulation are the Cdc25 phosphatases, which activate ...
“We are encouraged by the emerging data from our lung cancer programs, where systemically delivered Olvi-Vec continues to ...
TGFβ/ACTIVIN-SMAD2/3-EZH2 cooperates with OCT4 and NANOG in self-renewing hPSCs to keep CDKIs in an epigenetically poised state for rapid activation. Upon the initiation of endoderm differentiation ...
Rb1 loss may serve as a predictive biomarker to guide new targeted therapies for select breast cancers resistant to standard ...
A Targeted Methylation–Based Multicancer Early Detection Blood Test Preferentially Detects High-Grade Prostate Cancer While Minimizing Overdiagnosis of Indolent Disease Enzymatic conversion–mediated ...
In 2016, Colinda Scheele, a cancer biologist at Catholic University Leuven, was studying how chemotherapy affects breast cancer cells in mice. However, she observed an inconsistency: Some cell ...
A personal reflection on the promise and limits of CAR T therapy—its breakthroughs, failures, scientific bottlenecks, and what must change to truly save more lives.
A new Dartmouth study opens new avenues for understanding—and potentially manipulating—how cells decide to live or die. Scientists have long known that mitochondria—a cell's tiny power plants—pull ...
Despite a decade of people eyeing their phones like potential death traps, recent studies have put the final nail in the cell-phones-cause-cancer coffin. So, feel free to call, text, or scroll — your ...
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