AbstractNon apoptotic cell death programs particularly ferroptosis and cuproptosis are transforming how we understand cancer ...

Tumor growth unfolds within a tumor microenvironment (TME) defined by metabolic–immune crosstalk. Emerging evidence indicates that cancer cells not only reprogram glycolysis but also alter amino acid, ...

Up to 80 percent of patients with cancer struggle with cachexia, often called wasting syndrome, which is a condition characterized by the inability to gain or maintain body weight. One of the reasons ...

Mukherjee is a physician, researcher, and author. He has co-founded several biotechnology and health care companies focused on developing novel cancer treatments, including Faeth Therapeutics and ...

Tumor-associated macrophages (TAMs) are immune cells that tumors hijack to fuel their own growth and evade immune attack. A ...

A unique property of cancer cells is their ability to undergo metabolic reprogramming, during which they preferentially utilize aerobic glycolysis, glutaminolysis, mitochondrial respiration, and other ...

Ceramides—lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death—and their metabolites have been implicated in the development of cancer ...