Cells in the human body accumulate cancer-promoting mutations throughout their lifespan, yet these mutations rarely drive tumour formation. Tumours in a given tissue usually originate from a specific ...

The ability of mutations to cause cancer depends on how fast they force cells to divide, Sinai Health researchers have found. The study, led by Dr. Rod Bremner, a Senior Investigator at the ...

A hidden clue may explain why some mutated cells become cancerous and others don’t: how fast they divide. A new study from researchers at Sinai Health in Toronto reveals that the total time it takes ...

The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...