Investigators say the findings could lead to new therapeutic targets. New research is shedding light on 1 way chronic lymphocytic leukemia (CLL) cells are able to evade the body’s natural defenses.

Researchers of this new study found that treatment with venetoclax may be able to restore activation and proliferation of these cells, suggesting their plasticity can be leveraged for autologous ...

FOR YOUR REFERENCE: What Are Clinical Trials? Clinical trials determine whether a drug works in humans and whether it is safe and effective. For a drug to be approved for use, the Food and Drug ...

Preliminary safety and efficacy of PBCAR0191, an allogeneic, off-the-shelf CD19-targeting CAR-T product, in relapsed/refractory (r/r) CD19+ NHL. This is an ASCO Meeting Abstract from the 2021 ASCO ...

CAR-T treatments like Novartis’ Kymriah have proven effective in some B-cell-driven cancers, with one notable exception: chronic lymphocytic leukemia (CLL). Now, researchers at the University of ...

Phase II study of combination therapy with CHOP Interferon (IFN) alpha and rituximab (R) in chemo-naive patients (pts) with diffuse large B cell non-Hodgkin’s lymphoma (NHL) No significant financial ...

Lori A. Leslie, MD, an expert on chronic lymphocytic leukemia, provides a comprehensive overview of BTK inhibitors used in the treatment of CLL. Lori A. Leslie, MD: Let’s talk a bit more about Bruton ...

Please provide your email address to receive an email when new articles are posted on . Novel targeted therapies have become standard treatment for chronic lymphocytic leukemia due to their ability to ...

Monoclonal B-cell lymphocytosis is when your body produces an elevated number of identical B cells. In some cases, it can develop into chronic lymphocytic leukemia. Monoclonal B-cell lymphocytosis ...

Monoclonal B-cell lymphocytosis (MBL) is a condition in which a person has an excessive amount of abnormal B cells, which are a type of white blood cell known as lymphocytes. The number of abnormal B ...