Nature

Custom oligonucleotide array-based CGH: a reliable diagnostic tool for detection of exonic copy-number changes in multiple targeted genes

The frequency of disease-related large rearrangements (referred to as copy-number mutations, CNMs) varies among genes, and search for these mutations has an important place in diagnostic strategies.
Business Wire

Agilent Technologies Array CGH Platform Assures Quality of Cancer Cell Lines Used in Biomedical Research

SANTA CLARA, Calif.--(BUSINESS WIRE)--Agilent Technologies Inc. (NYSE:A) today announced that scientists using the company’s comparative genomic hybridization (CGH) technology have shown that cancer ...
Business Wire

Roche NimbleGen Launches CGH 12x135K Microarrays for Detection of Copy Number Variation

MADISON, Wis.--(BUSINESS WIRE)--Roche NimbleGen, Inc. has launched NimbleGen Comparative Genomic Hybridization (CGH) microarrays in a 12x135K format for analysis of DNA copy number variation.
GEN

Harnessing the Promise of Array CGH

In addition to the surprising revelation that our chromosomes harbor fewer genes than originally predicted, the Human Genome Project also unveiled that all individuals share approximately 99.9% of ...
Nature

Array CGH in patients with learning disability (mental retardation) and congenital anomalies: updated systematic review and meta-analysis of 19 studies and 13,926 subjects

The clinical significance of a copy number variant is usually determined either by observing whether the associated phenotype segregates along with the variant within a family, the rearrangement being ...
GEN

CGH for Detecting Copy Number Variation

Array CGH describes a technology in which microarrays comprised of well-defined DNA probes are used to screen DNA test samples to detect changes in sequence copy number. For whole-genome aCGH, genomic ...
technologynetworks

Agilent Technologies’ Custom-Designed CGH Microarray Used to Map Korean Genome

Agilent Technologies Inc. has announced that scientists using an Agilent custom-designed comparative genomic hybridization (CGH) array have sequenced the entire gene map of a Korean male. An ...
ascopubs.org

Determination of the use of CGH array to detect chromosomal instability (CIN)

Second-look hepatectomy after pharmacokinetic modulating chemotherapy (PMC) combination with hepatic arterial 5FU infusion and oral UFT in patients with unresectable hepatic colorectal metastases No ...
ascopubs.org

Array-based comparative genomic hybridization (CGH) identifies chromosomal imbalances between Interleukin-2 complete and non-responders

Predictors of survival in advanced renal cell carcinoma (RCC): Long-term results from Southwest Oncology Group trial S8949 No significant financial relationships to disclose. This is an ASCO Meeting ...
Medscape

Detection of Copy Number Alterations in Acute Myeloid Leukemia and Myelodysplastic Syndromes

Expert Rev Mol Diagn. 2012;12(3):253-264. Starczynowski et al. (2008) Low-risk MDS (44; IPSS ≤1.0) Discovery: array CGH with whole-genome BAC tiling array Validation: FISH of a selected locus Paired ...
Phgfoundation

Evaluation of array-CGH for chromosomal abnormalities in clinical practice

Microarray based comparative genomic hybridisation (array CGH) is a new technology with uses developing in various diagnostic areas within the NHS. One important context is the investigation of ...