A growing body of preclinical research points to the TIE2 receptor and its angiopoietin ligands as a promising drug target for brain blood vessel defects, including arteriovenous malformations, venous ...

Exposure of human cortical interneurons to hypoxia leads to decreased migration, a process that is likely altered in preterm infants and contributes to the increased risk for neurodevelopmental ...

"Now we know there are internal problems with blood vessels in the brain," said study leader Leslie Thompson, UCI professor of psychiatry & human behavior and neurobiology & behavior. "This discovery ...