An investigation by researchers from Case Western Reserve University School of Medicine in the US has filled in a missing link between the toxic build-up of proteins in the neurodegenerative condition ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, ...

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break ...

Knowing which lysosomal proteins are enriched in which brain cell types will help better understand contribution to neurological disorders.

Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in ...

Memory dysfunction in Alzheimer's disease may be linked to impairment in how the brain replays our recent experiences while we are resting, according to a new study in mice by University College ...

The federal government is looking for researchers who can, in 5 years, develop stem cell treatments to repair brain damage caused by stroke, neurodegeneration, and trauma. The Functional Repair of ...

Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer’s disease and preserves cognitive function ...

Major depression is not only a crisis of mood, it is also a crisis of biology that reshapes the brain itself. As genetic tools sharpen, scientists are now tracing how inherited risk for depression is ...

In mice, blocking heart-to-brain signals improved healing after a heart attack, hinting at new targets for cardiac therapy.

While diet changes have long been credited for long-term health benefits, it's not often for brain health. A new UNC study ...