There is a complex pathological relationship between diabetes and osteoporosis, two of the most common chronic diseases worldwide.

Blood cancers such as leukemia are caused by genetic changes in the blood-forming stem cells of the bone marrow. Scientists at the University Medical Center Mainz have now shown how chronic ...

In a recent study, Associate Professor Makoto Ikeya (Department of Clinical Application) and his team of researchers successfully established a method to generate jawbone-like organoids (mini-organs) ...

Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver ...

Bone morphogenetic proteins (BMPs) are secreted growth factors belonging to the transforming growth factor-β superfamily that orchestrate the formation, growth and maintenance of the vertebrate ...

Skeletal stem cells (SSCs) are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques ...

Bone formation and maintenance depend on the coordinated activity of osteoblasts, osteoclasts and osteocytes, whose differentiation and function are governed by tightly regulated gene networks.

Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, causing pain, fractures, and decreased quality of life. These conditions often ...

Bone spurs are smooth bony projections that form along joint edges, often due to ageing, osteoarthritis, injury, or ...

Pilot studies have shown encouraging results that are supporting the company’s pre-IND enabling development, marking a critical step toward clinical translation of the Bone Marrow Organoid technology ...