Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles ...

Researchers found that mice lacking membrane ERα signaling in osteoblast lineage cells had significantly lower cortical bone mass, highlighting the pathway’s critical role in maintaining the strength ...

Our body's "blood factory" consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this ...

Tooth loss and bone degeneration are problems that modern medicine still struggles to fix. Data from the National Bone Health Policy Institute shows that 10 million Americans over the age of 50 have ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

Dr. Matthew Greenblatt will receive the prestigious Paul-Gallin Trailblazer Prize for Physician-Scientists in recognition of his discovery of distinct types of bone-building stem cells in different ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

Cell therapy is an advanced biomedical approach that utilizes living cells as therapeutic agents to treat disease or repair tissue. 4 Scientists isolate cells from a patient or a healthy donor and ...