Experts from Capsugel and Catalent discuss the rationale of using lipid0basd formulations to improve the oral bioavailability of poorly soluble drugs. Poor solubility remains an ongoing challenge in ...

The pH effect encountered with oral oncology medication can be overcome with amorphous solid dispersions. Oral delivery is the preferred route of drug product administration for maximizing patient ...

The pharmaceutical industry is entering an inflection point driven by the recognition that highly potent cancer drugs are only as effective as their ability to reach tumors with sufficient ...

SEATTLE & BETHLEHEM, Pa.--(BUSINESS WIRE)--Spoke Sciences, Inc. (Spoke), an ingredient technology company developing innovative approaches to provide better, safer, and more reliable functional ...

Oral administration is by far the most convenient and acceptable route of drug administration, especially for patients with chronic diseases who require long-term medication 13. However, the absolute ...

The physical stability and bioavailability of a fixed-dose combination (FDC) drug containing four anti-TB medicines — rifampicin, isoniazid, pyrazinamide and ethambutol — has been vastly improved from ...

Single atom 'O' to 'S' substitution in cyclic peptides improves their membrane permeability and bioavailability. This study paves the way for developing next-generation peptide-based therapeutics.

Bioavailability is a key parameter of a drug’s behavior and is determined during pre-clinical development. It is the fraction of a compound that reaches systemic circulation and is important for ...

PEGASUS generates permeable macrocyclic peptides, offering new promise for a modality that can combine the properties of a biologic in a pill ...

Prodrugs are bioreversible derivatives of drug molecules that must undergo an enzymatic and/or chemical transformation in vivo to release the active parent drug, which can then exert its desired ...

NEW YORK, Oct. 27, 2025 /CNW/ -- The global oncology market is rapidly shifting toward smarter drug-delivery systems that enhance efficacy, reduce toxicity and improve patient outcomes. Traditional ...