Prior biliary tract surgery was previously considered a contraindication for laparoscopic biliary tract reoperation. However, it is now widely performed in patients with or without prior operations ...

Overall mortality was low (n = 7), and the frequency of various complications varied by the type of procedure used to clear stones from the biliary tract. With respect to avoiding postoperative ...

ctDNA is a valuable prognostic biomarker for relapse in early-stage BTC, outperforming carbohydrate antigen 19-9 levels. ctDNA monitoring can detect molecular recurrence earlier than standard ...

Phase 3, randomized study of pembrolizumab (pembro) vs best supportive care (BSC) for second-line advanced hepatocellular carcinoma (HCC): KEYNOTE-240. This is an ASCO Meeting Abstract from the 2017 ...

Keytruda, combined with gemcitabine and cisplatin, is approved for advanced biliary tract cancer, showing a 17% reduction in death risk compared to chemotherapy alone. The KEYNOTE-966 trial indicated ...

Gallbladder cancer and cholangiocarcinoma are different types of biliary tract cancer. They affect the same system in the body and cause similar symptoms, but they may require different treatments.

Credit: Getty Images. The sBLA is supported by data from the KEYNOTE-966 trial. The Food and Drug Administration (FDA) has accepted for review the supplemental Biologics License Application (sBLA) for ...

The approval, which is based on results from the phase 3 KEYNOTE-966 trial, marks the sixth indication for pembrolizumab in gastrointestinal cancer. The FDA has approved pembrolizumab (Keytruda; Merck ...