The US Food and Drug Administration (FDA) issued a draft guidance on Friday to assist sponsors in using Bayesian methods to support the safety and effectiveness of new drugs in clinical trials. These ...

The FDA's move to incorporate Bayesian statistical methods into clinical trials of drugs and biologics garnered special treatment in JAMA this week. JAMA published three perspectives -- two welcoming ...

Approaches for statistical inference -- The Bayes approach -- Bayesian computation -- Model criticism and selection -- The empirical Bayes approach -- Bayesian design -- Special methods and models -- ...

Empirical Bayesian methods occupy a unique position at the interface of frequentist and Bayesian paradigms by estimating prior distributions directly from observed data. This approach preserves the ...

A Bayesian particle Gibbs framework enables unbiased spike time inference with millisecond resolution and jointly estimates uncertainties in both spike timing and model parameters from fast calcium ...