We constructed a series of mutant forms of cyclin B1, in which these four serines were replaced by glutamate to mimic phosphorylation. When each of the serines, or the first two or the last two, were ...
The cyclin-dependent kinase 1 (Cdc2)/cyclin B1 complex performs cardinal roles for eukaryotic mitotic progression. Phosphorylation of four serine residues within cyclin B1 promotes the rapid nuclear ...
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