Bioassay variability can pose significant challenges due to laboratory conditions, instrumentation, analytical software, cell culture performance and reagent sourcing. These inconsistencies can impact ...

In summary, the development of the yeast two-hybrid assay has helped molecular and cell biologists in their quest to understand the cell, at the level of single proteins or a few proteins at a time—a ...

Method-transfer kits help simplify analytical method transfer for global site certifications. Method transfers are required to enable critical medications to reach ...

The article proposes an integration of method validation, transfer, and verification process into the overall lifecycle management process. The US Pharmacopeial Convention (USP) released a general ...

Measuring Enzyme Kinetic Parameters with the ITC Universal Enzyme Assay Method Enzymes are important in drug discovery and development since they constitute approximately one-half of all known drug ...

The Total Oxidizable Precursor assay has identified higher levels of PFAS in birds than previously recorded. A research team from the Norwegian University of Science and Technology (Trondheim, Norway) ...

Cell death in vitro can be induced by several distinct mechanisms depending upon the type and potency of the stimulus. Biological variables present a challenge to rapid and efficient characterization ...