Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...
PCR primers were designed in an average distance of 0.7 kb upstream and downstream of each predicted junction and amplifications were performed using standard protocols of Promega Master Mix (Promega ...
Recently, microarray-based comparative genomic hybridization (array-CGH) has emerged as a very efficient technology with higher resolution for the genome-wide identification of copy number alterations ...
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