It has been difficult to devise a practical clinical approach to reliably separate simple urinary tract infections (UTIs) from UTIs that also involve the kidneys (acute pyelonephritis). The gold ...

I often find myself under- or overestimating the incidence of certain nephrology-related conditions. I know this "error" is, in part, due to an "exposure bias" in my practice. I tend to overestimate ...

"The five factors with the highest odds of developing APN included obstructive and reflux uropathy, presentation to an acute care facility, urinary retention, history of UTI, and renal comorbidities.

THE clinical diagnosis of pyelonephritis is frequently overlooked, and the disparity between the clinical and post-mortem findings in this infection has been emphasized repeatedly. 1–4 The failure of ...

Acute pyelonephritis is a bacterial infection that causes inflammation in the kidneys. This is an unexpected and serious kidney infection in which the urinary tract infection travels from the bladder ...

Tebipenem pivoxil hydrobromide is an orally bioavailable carbapenem with activity against uropathogenic Enterobacterales. Oral tebipenem pivoxil hydrobromide (HBr), a carbapenem, is as effective as ...

Guidelines for the management of acute pyelonephritis in children currently recommend that oral antibiotic therapy is preceded by parenteral treatment with a third-generation cephalosporin. This ...

Suffering from urinary tract infection? You could be at a risk of developing kidney infection. Here's everything you need to know about it Given that the kidneys are closely associated with the ...

To determine the frequency and clinical significance of ultrasonographically detectable alterations in renal volume and anatomy that are associated with acute pyelonephritis, 25 women underwent renal ...

intravenous antibiotics Cefepime-enmetazobactam may be more effective than piperacillin-tazobactam in treating complicated UTI and acute pyelonephritis caused by organisms that produce ...

Spero Therapeutics announced that the Food and Drug Administration (FDA) has granted Fast Track designation for SPR994 (tebipenem pivoxil hydrobromide) for the treatment of complicated urinary tract ...